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The People Side of AI

Hello 👋
Welcome to the 118th edition of the Re:VITALIZE Newsletter for founders and friends.
We want to make sure the content we put together is useful. If you have a question you’d like Gale to answer in an upcoming newsletter, please let us know!
New readers can subscribe here. ✨
Gale’s Thoughts on the Market & Investing
We often ignore a key point in the AI conversation: the next era of value creation won’t come from the technology itself. It will come from the humans who know how to harness it.
The people who can shepherd, facilitate, and champion AI and data adoption — the ones who translate capability into outcomes — will greatly influence which companies thrive in the years ahead.
A few weeks ago, a student emailed me asking for an unpaid, remote internship. I replied to see if they’d be open to tackling some AI projects for VITALIZE. Their response: “I’m afraid I’m not qualified to work on AI.” And while I appreciated the honesty, it made me pause. No one is really qualified yet.
This student’s email had said, “I believe my background in quantitative research and strong analytical skills would allow me to add meaningful value to your team. I would be eager to contribute through market analysis, diligence support, and even preliminary sourcing or deal preparation.”
Going forward, we won’t just hire analysts and associates at VC funds to write memos or build reports. We’ll hire them to build tools that make those processes faster and better. Every item this student listed — market analysis, diligence, sourcing — is already being heavily augmented with AI. You don’t need to be an engineer to experiment with AI tools. You just need to be open-minded enough to try and figure out how AI can improve existing workflows. I don’t see a future world in VC where entry-level talent isn’t adept at AI and data.
Several of my VC friends have recently shared stories of incredibly talented, product-focused consultants or students who are building AI solutions that replace weeks of work in minutes. They figure it out. Quickly. I haven’t yet met one of these exceptional superstars for VITALIZE’s projects, but if you know someone, please reach out. These early adopters who dive in and just figure it out will be the ones best positioned on this AI ride we all find ourselves on.
We’re seeing the people side of AI and data take shape across our portfolio, too. One of our companies is hiring a data scientist to build a complex data graph designed to extract value from networks — a system that, if done well, could redefine how people connect and collaborate. It’s a single hire, but a pivotal one. The work this person does will shape the company’s entire data strategy and long-term potential. This hire could make all the difference.
As AI becomes embedded across every sector, the differentiator will be the people — all the way from entry-level analysts to heads of data strategy. The tech isn’t nearly advanced enough to succeed without these architects and champions who lead the way.
On a related note: I started this blurb with AI prompts and examples from previous newsletters, and I still had to revise about 90% of it. We just aren’t there yet without humans in the loop.
Recent VITALIZE Investments
One is closing and will be announced soon!
A VITALIZE Win
Magic Door (Fund II) closed its $4.5M seed round!!
Work Insights
Some articles we like on work insights:
U.S. Begins Shutdown That Could Lead to Mass Layoffs and Service Cuts (NYT)
How CHROs Can Make Culture Tangible Every Day (Gartner)
Why Government Shutdown Might Be The Best Career Wake-Up Call (Forbes)
How human-centric AI can shape the future of work (WEF)
More Women Are Leaving the Workforce. Here’s What You Can Do About It (Inc.)
Why Gen Z can’t afford to specialize at work (Fast Company)
Our Content Picks for Founders
🥇 First Time Founder Playbook
Advice to first-time founders:
- marketing from day 0
- mvp = single killer feature (no more)
- bake distribution in-app
- subs >> one-time payments
- launch in month 1.. ambitious but doable
- re-launch weekly
- scale: from $1 to $100, $1k, $10k mrr
- seo, seo, seo (+track— Saïd Aitmbarek (@SaidAitmbarek)
6:49 PM • Oct 2, 2025
🥈 Seed to an Urgency
After raising your seed, the biggest driver of whether you’ll raise a Series A is the speed at which you iterate. Seed capital buys you time, but not much. For most founders, you have about two years of runway before the money runs out.
Here’s the math: scaling after you’ve hit
— Hadley (@Hadley)
11:36 PM • Oct 1, 2025
🥉 Co-Founder Fallout Rising
Co-founder disputes are by far the #1 cause of company failure I’ve seen at the pre-seed/seed stage.
You’re much better off (and less risky) solo-founding than entering a brittle partnership. Co-founders need to be 100% committed to each other, not marriages of convenience
— arian ghashghai (@arian_ghashghai)
5:41 PM • Oct 3, 2025
Our Content Picks on Investing
🥇 Why VCs Avoid Hardware
Lots of investors are getting bashed right now for not investing in hardware.
Let me put you in their shoes:
VC funds have agreements with their own investors (LPs). Those agreements often specify focus areas that must be respected for the lifetime of the fund, and hardware
— Hubert Thieblot (@hthieblot)
5:57 PM • Oct 2, 2025
🥈 $20M+ VC Lesson
venture is a strange and unpredictable business
one of the first deals I did as a VC just raised a $20M+ Series B
we invested at seed, then divested and then I personally invested at A.
at one point we had no idea if the company was functioning and alive as there was no
— adriel (@adrielyong)
12:20 AM • Oct 9, 2025
🥉 The VC Time Horizon
Venture capital is the best job in the world for either 2 years or 10 years, but not for any stints in between.
2 years to learn the inside game of how funding is allocated, or 10 years to harvest the fruits of both returns, but well hidden secrets to venture that are only
— Peter / ‘pet3rpan’ (@pet3rpan_)
10:21 AM • Sep 7, 2025
VITALIZE Portcos in the News
Enklu (Fund I) delivers next‑generation AR entertainment through a first-of-its-kind holographic haunted house, and was featured in The AI Journal
Genomenon (Fund I) announced its strategic partnership with Compass Bioinformatics to transform genomic diagnostics, as featured in Yahoo!Finance
Jurny (Fund I) was named a finalist in Octane's 2025 High Tech Awards for Best AI Innovation
Suma Wealth (Fund I) partners with the City of Los Angeles and SALEF to launch a free bilingual app called SUMA.
Leadsales (Fund II) has been selected as part of the Mexico Early Stage 100
Palla (Fund II) was named one of the top remittances companies and startups in the United States by F6S
PeakMetrics (Fund II) released a case study on AI-Driven Bots, which was featured and referenced by Gizmodo and The Wall Street Journal
Check out open jobs at VITALIZE portfolio companies
Written by the team at VITALIZE, a venture capital firm investing in U.S.-based B2B software founders innovating in WorkTech. Find us on LinkedIn, X, and YouTube.
This is the 118th edition of the Re:VITALIZE newsletter! ✨